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Allele : Tg(Myh6-Agtr1a)4-7Vjd transgene insertion 4-7, Victor J Dzau

Primary Identifier  MGI:3664306 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Agtr1a)4-7Vjd
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of the murine alpha-myosin heavy chain promoter driving the expression of mouse Agtr1a (angiotensin II type 1 receptor). Additionally, a tyrosinase minigene was co-injected with the transgene construct to allow visual identification of transgenic offspring coat color. Radioligand binding studies and RT-PCR confirm the specific expression of the transgene in cardiomyocytes.
  • mutations:
  • Insertion
  • synonyms:
  • alphaMHC-AT1,
  • alphaMHC-AT1 M4/7,
  • alphaMHC-AT1,
  • alphaMHC-AT1 M4/7
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories