Primary Identifier | MGI:3664306 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Myh6-Agtr1a)4-7Vjd |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of the murine alpha-myosin heavy chain promoter driving the expression of mouse Agtr1a (angiotensin II type 1 receptor). Additionally, a tyrosinase minigene was co-injected with the transgene construct to allow visual identification of transgenic offspring coat color. Radioligand binding studies and RT-PCR confirm the specific expression of the transgene in cardiomyocytes. |