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Allele : Klhl1/Atxn8os<tm1Mdk> kelch-like 1; targeted mutation 1, Michael D Koob

Primary Identifier  MGI:3664538 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Klhl1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into the transcription start site of Klhl1, which is also the upstream region of the polyA signal of Klhl1as. A neo cassette flanked with 2 FRT sites and a 3' loxP site were inserted into the first intron of Klhl1, which is downstream of the transcription start site of Klhl1as. Crossing with mice that express FLP in the germline resulted in the removal of the neo, leaving exon 1 of Klhl1 flanked by loxP sites and the complete coding sequence for Klhl1as flanked by loxP sites.
  • mutations:
  • Insertion
  • synonyms:
  • Klhl1/Klhl1as<tm1Mdk>,
  • Klhl1<flox>,
  • Klhl1<flox>,
  • Klhl1/Klhl1as<tm1Mdk>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories