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Allele : Ms4a2<tm1Knt> membrane-spanning 4-domains, subfamily A, member 2; targeted mutation 1, Jean-Pierre Kinet

Primary Identifier  MGI:3664659 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ms4a2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  ES cell line = D3 (129S2/SvPas) or E14Tg2a (129P2/OlaHsd).
molecularNote  Exons IV-VI were replaced with a neomycin selection cassette. FceRI expression on bone marrowÐderived cultured mast cells was abolished in homozygous mice, indicating that this gene is required for cell surface expression of high-affinity IgE receptors.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • FcRbeta<->,
  • FcRbeta<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories