Primary Identifier | MGI:3664659 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ms4a2 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = D3 (129S2/SvPas) or E14Tg2a (129P2/OlaHsd). |
molecularNote | Exons IV-VI were replaced with a neomycin selection cassette. FceRI expression on bone marrowÐderived cultured mast cells was abolished in homozygous mice, indicating that this gene is required for cell surface expression of high-affinity IgE receptors. |