Primary Identifier | MGI:3664862 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Bdnf |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A V66M mutation was introduced into the prodomain via homologous recombination. The PGK-neo selection cassette was removed by crossing to a Cre strain with expression at one-cell zygote stage. Total expression of protein in brain lysates is similar to wild-type. |