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Allele : Bdnf<tm1Flee> brain derived neurotrophic factor; targeted mutation 1, Francis S Lee

Primary Identifier  MGI:3664862 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Bdnf
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A V66M mutation was introduced into the prodomain via homologous recombination. The PGK-neo selection cassette was removed by crossing to a Cre strain with expression at one-cell zygote stage. Total expression of protein in brain lysates is similar to wild-type.
  • mutations:
  • Insertion
  • synonyms:
  • BDNF<Met>,
  • BDNF<M>,
  • BDNF Val66Met,
  • BDNF<Met>,
  • BDNF Val66Met,
  • BDNF<M>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

31 Publication categories