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Allele : Nlrp3<tm1Flv> NLR family, pyrin domain containing 3; targeted mutation 1, Richard A Flavell
Primary Identifier  MGI:3686871 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nlrp3
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES-LacZ-MC1-neo cassette replaced exons 1 and 2. RT-PCR confirmed absence of transcript in mutant splenocytes.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nalp3<->,
  • Cias1<->,
  • Nalp3<->,
  • Nlrp3<->,
  • cryopyrin,
  • Cias1<->,
  • Nlrp3<->,
  • cryopyrin
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

198 Publication categories





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