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Allele : Apc<tm2.1Rak> APC, WNT signaling pathway regulator; targeted mutation 2.1, Raju Kucherlapati

Primary Identifier  MGI:3688437 Allele Type  Targeted
Attribute String  Null/knockout Gene  Apc
Transmission  Germline Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL
Is Recombinase  false Is Wild Type  false
molecularNote  This allele is a derivative of Apctm2Rak in which the loxP-flanked exon 14 sequences have been deleted by Cre-mediated recombination in the germline. A single loxP site remains in place of exon 14 and flanking intronic sequences. Loss of exon 14 is predicted to introduce a frameshift mutation and a premature stop codon, resulting in a truncated protein.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Apc<delta580>,
  • Apc<delta580>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories