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Allele : Trp53<tm3Xu> transformation related protein 53; targeted mutation 3, Yang Xu

Primary Identifier  MGI:3687352 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Lysine codon 317 (AAA) in exon 9 was changed to arginine (AGA) (p.K317R). The LoxP site flanked neomycin resistance gene cassette that was inserted into intron 4 was removed via Cre-mediated recombination. This mutation prevents acetylation of the residue in the encoded peptide.
  • mutations:
  • Single point mutation
  • synonyms:
  • p53<K317R>,
  • p53<K317R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories