| Primary Identifier | MGI:3687451 | Allele Type | Targeted |
| Attribute String | Null/knockout, Recombinase | Gene | Cd79a |
| Transmission | Germline | Strain of Origin | BALB/c |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | Exons 2 and 3 of the Cd79a gene were replaced with a cDNA encoding a mammalian codon-optimized cre (hCre) followed by an SV40 poly(A) signal. Exon 1 was truncated to remove the Cd79a ATG start codon, and a tk-neo cassette flanked by FRT sites was introduced 3' to hCre. The neo cassette was deleted in chimeras by crossing to Flpe deleter mice. |
