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Allele : Fktn<tm2(FCMD)Ttd> fukutin; targeted mutation 2, Tatsushi Toda

Primary Identifier  MGI:3690337 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Fktn
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 10 was removed from the locus via Cre mediated expression following the insertion of lox71 and loxP sites. Human FCMD exon 10 cDNA from a patient with Fukuyama Congenital Muscular Dystrophy with the causative retrotransposon was inserted between the lox66 and loxP sites of the targeting construct. Transcript expression level is 5% to 10% of normal.
  • mutations:
  • Insertion
  • synonyms:
  • Ftkn<Hp>,
  • Ftkn<Hp>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories