Primary Identifier | MGI:3691852 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tdrd1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to disrupt the first ATG of transcript variants 1-3 and replace the promoter of variant 4 by the insertion of a neo in the ATG in exon 3. In testes, a truncated Tdrd1 mRNA was detected, but Western blot analysis showed absence of any Tdrd1 protein. |