Primary Identifier | MGI:3695417 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Abcg1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Deltagen |
description | When used in bone marrow transplant into Ldlrtm1Her homozygous mice, Abca1tm1Jdm Abcg1tm1Dgen homozygous cells accelerate the development of atherosclerosis. (J:130777) |
molecularNote | A targeting vector was used to replace 21 bp, encoding seven amino acids (GPSGAGK), in exon 3 with a floxed IRES-lacZ-neo-pA cassette. |