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Allele : Abcg1<tm1Dgen> ATP binding cassette subfamily G member 1; targeted mutation 1, Deltagen

Primary Identifier  MGI:3695417 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Abcg1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Deltagen
description  When used in bone marrow transplant into Ldlrtm1Her homozygous mice, Abca1tm1Jdm Abcg1tm1Dgen homozygous cells accelerate the development of atherosclerosis. (J:130777)
molecularNote  A targeting vector was used to replace 21 bp, encoding seven amino acids (GPSGAGK), in exon 3 with a floxed IRES-lacZ-neo-pA cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Abcg1<->,
  • Abcg1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

60 Publication categories