| First Author | Swardson CJ | Year | 1997 |
| Journal | Exp Parasitol | Volume | 86 |
| Issue | 2 | Pages | 102-9 |
| PubMed ID | 9207740 | Mgi Jnum | J:41574 |
| Mgi Id | MGI:894061 | Doi | 10.1006/expr.1997.4154 |
| Citation | Swardson CJ, et al. (1997) Plasmodium yoelii: resistance to disease is linked to the mtv-7 locus in BALB/c mice. Exp Parasitol 86(2):102-9 |
| abstractText | We have identified congenic mouse strains that differ dramatically in resistance to infection with the murine malaria parasite Plasmodium yoelii 17X. After infection, BALB/c mice develop severe anemia and a high degree of parasitemia which sometimes results in death. The mtv-7 congenic strain BALB.D2.mls(a), however, develops only a mild degree of anemia and parasitemia. In this paper we describe the course of the disease and discuss the potential role of mtv-7 and linked loci in control of this infection. These mice differ in their response to anemia, which may contribute to their differential susceptibility to disease; however, no influence of mtv-7 reactive T cells was documented. (C) 1997 Academic Press. |
