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Allele : Tg(ABCG5,ABCG8)63Ssf transgene insertion 63, Silvia Santamarina-Fojo

Primary Identifier	MGI:3696674	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(ABCG5,ABCG8)63Ssf
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

The transgene is BAC clone 26313 (Incyte Genomics) containing the complete human ABCG5 and ABCG8 genes and flanking DNA. Approximately 63 copies of the BAC clone were inserted into the mouse genome.

mutations:
Insertion

synonyms:
hABCG5+G8-tg 63c,
hABCG5+G8-tg 63c,
G5/G8-Tg,
G5/G8-Tg

earliestPublication:
Wu JE, et al. (2004) Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice. J Biol Chem 279(22):22913-25

1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

2 Publication categories

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