| Primary Identifier | MGI:3698956 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change, Reporter | Gene | Ager |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An EGFP reporter gene followed by a single loxP site was inserted into intron 1 in reverse transcriptional orientation to the gene. A neomycin selection gene followed by a single loxP site and a thymidine kinase promoter were inserted into intron 7. Tissue specific cre mediated recombination deletes exons 2-7 and brings the thymidine kinase promoter into proximity of the EGFP gene conditionally activating transcription and expression of the reporter. |
