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Allele : Sox10m3<C57BL/6J> Sox10Dom modifier 3; C57BL/6J

Primary Identifier	MGI:3699510	Allele Type	QTL
Gene	Sox10m3	Inheritance Mode	Other (see notes)
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

description	Agln2 exhibits additive inheritance.
molecularNote	This allele confers decreased aganglionosis penetrance/severity and decreased affected gut length compared to C3H/HeJ.

earliestPublication:
Owens SE, et al. (2005) Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease. Hum Mol Genet 14(11):1549-58

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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