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Allele : Trp53<tm6Wahl> transformation related protein 53; targeted mutation 6, Geoffrey M Wahl

Primary Identifier  MGI:3699247 Allele Type  Targeted
Attribute String  Not Specified Gene  Trp53
Transmission  Germline Strain of Origin  129S4/SvJae-Tg(Prm-cre)70Og
Is Recombinase  false Is Wild Type  false
molecularNote  Proline codons 79 (CCA), 82 (CCT), 84 (CCA) and 87 (CCA) in exon 4 were changed to alanine (GCA, GCT, GCA, GCA) (p.P79A, p.P82A, p.P84A, p.P87A). The loxP site flanked neomycin resistance gene cassette that was inserted into intron 6 was removed through subsequent Cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • P53<AXXA>,
  • P53<AXXA>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories