|  Help  |  About  |  Contact Us

Allele : Ncf4<tm1Pth> neutrophil cytosolic factor 4; targeted mutation 1, Phillip T Hawkins

Primary Identifier  MGI:3701805 Allele Type  Targeted
Gene  Ncf4 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The sequence of codon 58 was altered from CGC to GCC resulting in an arginine to alanine amino acid substitution (p.R58A) that disrupts PtdIns3P binding. A self-excising floxed tACE-Cre expression module and neo cassette was inserted into intron 3, and was removed by cre-mediated excision specifically in the testis during breeding of the chimeras.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • p40<phoxR58A>,
  • p40<phoxR58A>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories