| Primary Identifier | MGI:3701943 | Allele Type | Targeted |
| Attribute String | Conditional ready, Inserted expressed sequence, No functional change | Gene | Kmt2a |
| Transmission | Germline | Strain of Origin | 129S/SvEv |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = L4. |
| molecularNote | A cassette containing a splice acceptor, the open reading frame of Sh3gl1, an IRES-EGFP and an FRT-flanked neomycin resistance cassette was flanked by inward facing loxP sites and inserted in opposite orientation between exon 8 and 9. Flp-mediated recombination removed the selection cassette. Cre-mediated inversion is required to achieve expression of the fusion at exon 8. The fusion products mimick a fusion found in human patients with leukemia. |
