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Allele : Igl<tm2Bgmn> immunoglobulin lambda chain complex; targeted mutation 2, Marianne Bruggemann

Primary Identifier	MGI:3701068	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Igl
Transmission	Germline	Strain of Origin	129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase	false	Is Wild Type	false

molecularNote

ES cells containing the C1 to C3 deletion were transfected with a construct designed to insert a floxed neo cassette into C2. This resulted in silencing of C2.

mutations:
Deletion

cellLines:
Not Specified

synonyms:
C1<->C2<->C3<->,
C1<->C2<->C3<->,
ES2.4,
ES2.4

earliestPublication:
Zou X, et al. (2003) Block in development at the pre-B-II to immature B cell stage in mice without Ig kappa and Ig lambda light chain. J Immunol 170(3):1354-61

1 Feature

Trail: Allele

Genome

0 Expresses

5 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele

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Message:	---- Current page: ---- /mousemine/report.do?id=74634451&trail=%7C74634451 ---- Current query: ---- <query name="" model="genomic" view="Gene.primaryIdentifier Gene.symbol Gene.name Gene.sequenceOntologyTerm.name Gene.chromosome.primaryIdentifier" longDescription=""><constraint path="Gene" op="IN" value="Mouse DNA repair genes 2013-01-06"/></query>

MouseMine

Allele : Igl<tm2Bgmn> immunoglobulin lambda chain complex; targeted mutation 2, Marianne Bruggemann

External Links

1 Feature

Genome

0 Expresses

5 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories