Primary Identifier | MGI:3701426 | Allele Type | Transgenic |
Attribute String | Null/knockout | Gene | Nmur2 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A retroviral vector was inserted into the third intron and contained a splice acceptor, termination codons in all reading frames, a selection marker and a transcription terminator. This design would interrupt the transcript before exon 4, which contains TM7 of the 7-transmembrane domain and the C-terminal domain. RT-PCR confirmed absence of wild-type transcript in mutants. |