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Allele : Tg(Prm1-cre)1Mrc transgene insertion 1, Mario R Capecchi

Primary Identifier	MGI:3702329	Allele Type	Transgenic
Attribute String	Recombinase	Gene	Tg(Prm1-cre)1Mrc
Strain of Origin	C57BL/6	Is Recombinase	true
Is Wild Type	false

molecularNote

The mouse promoter was used to drive spermatid-specific expression of the P1 cre cistron followed by a human growth hormone 3' flanking sequence. Several lines were created (no line names given). Expression of the cre transgene in testes was confirmed by RNase protection assay.

mutations:
Insertion

synonyms:
Prm1-Cre-hGH,
Prm1-Cre-hGH

earliestPublication:
Schmidt EE, et al. (2000) Illegitimate cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proc Natl Acad Sci U S A 97(25):13702-7

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

3 Publication categories

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