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Transgene : Tg(CAG-Bgeo,-TEL/AML1,-EGFP)A6Lbe transgene insertion A6, Corinne G Lobe
Primary Identifier  MGI:3703086 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: Homozygotes die in utero. While pan expression of TEL-AML1 after crossing with cre leads to embryonic lethality (E7.5), hematopoietic- and endothelial-specific expression leads to malignancy in B- and T- lymphoid cells and secondary mutations that closely resemble human TEL-AML1 associated leukemia. [provided by MGI curators]
  • synonyms:
  • iZ/EG-TEL-AML1,
  • transgene insertion A6, Corinne G Lobe,
  • Tg(ACTB-Bgeo,-TEL/AML1,-EGFP)A6Lbe,
  • Tg(CAG-Bgeo,-TEL/AML1,-EGFP)A6Lbe
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