| Primary Identifier | MGI:3704871 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(Ins1-EGFP)1Hara |
| Strain of Origin | CD-1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A transgenic construct containing the coding region of the EGFP gene and a 2.1kb sequence of the human growth hormone to confer high expression of the EGFP, under the control of the mouse insulin 1 gene promoter (a 8.5 kb region including -8.5 to +12 bp relative to the transcriptional start site) was injected into fertilized CD1 mouse eggs. Founder line 1 was subsequently established. Fluorescence is detected in tissues where insulin I is normally expressed; fluorescent protein expression in pancreatic beta-cells is evident from embryonic day (E)13.5 through adult. |
