First Author | Mamalaki C | Year | 1992 |
Journal | Proc Natl Acad Sci U S A | Volume | 89 |
Issue | 23 | Pages | 11342-6 |
PubMed ID | 1360667 | Mgi Jnum | J:120505 |
Mgi Id | MGI:3706706 | Doi | 10.1073/pnas.89.23.11342 |
Citation | Mamalaki C, et al. (1992) Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice. Proc Natl Acad Sci U S A 89(23):11342-6 |
abstractText | Injection of mice transgenic for a class I major histocompatibility complex-restricted T-cell receptor with a soluble peptide antigen from influenza virus nucleoprotein results in clonal depletion of double-positive immature thymocytes in the thymus and activation of mature T cells in the periphery, accompanied by a transient up-regulation of the T-cell receptor and CD3 and CD8 coreceptor molecules. |