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Allele : Mapk14<tm1.1Dvb> mitogen-activated protein kinase 14; targeted mutation 1.1, Dmitry V Bulavin

Primary Identifier	MGI:3706998	Allele Type	Targeted
Gene	Mapk14	Transmission	Germline
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

Regulatory sites Thr180 and Tyr182 are replaced by alanine and phenylalanine, respectively. A floxed neo cassette inserted downstream of exon 8 was removed by germ line, cre mediated recombination.

mutations:
Nucleotide substitutions

cellLines:
Not Specified

synonyms:
p38alpha<ki>,
p38<AF>,
p38<AF>,
p38alpha<ki>

earliestPublication:
Shreeram S, et al. (2006) Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase. J Exp Med 203(13):2793-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

15 Publication categories

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