Primary Identifier | MGI:3707160 | Allele Type | Targeted |
Attribute String | Dominant negative, Inserted expressed sequence | Gene | Tcf12 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A series of point mutations were inserted into the basic DNA-binding region in exon 19 (coding exon 18), changing RLR to GHG (R611G, L612H, R613G). A floxed neomycin resistance gene was inserted into the locus and subsequently removed via transient cre expression. |