| Primary Identifier | MGI:3711216 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Elovl4 |
| Transmission | Germline | Strain of Origin | 129/SvEv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert a floxed neo and DNA construct containing a pathogenic 5-bp deletion ((797-801_AACTT) and two point mutations in exon 6. This construct resulted in a truncated protein which contains the same aberrant 8-amino acid C-terminus encoded by the human pathogenic allele. The floxed neo was subsequently removed via cre mediated recombination. |
