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Allele : Slc4a4<tm1Ges> solute carrier family 4 (anion exchanger), member 4; targeted mutation 1, Gary E Shull

Primary Identifier	MGI:3710188	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Slc4a4
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Part of exon 9 was replaced with a neomycin resistance gene. Absence of transcript was confirmed by Northern blot of mutant kidney, small intestine and colon.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Nbc1<->,
NBCe1<->,
Nbc1<->,
NBCe1<->

earliestPublication:
Gawenis LR, et al. (2007) Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter. J Biol Chem 282(12):9042-52

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

20 Publication categories

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