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Allele : Braf<tm1.1Wds> Braf transforming gene; targeted mutation 1.1, William D Snider

Primary Identifier  MGI:3711007 Allele Type  Targeted
Attribute String  Null/knockout Gene  Braf
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was removed by cre mediated recombination in the germline. Deletion of exon 3 was expected to cause a reading frame shift and introduce a translational stop codon at position 132, truncating the RBD, CRD and kinase domains. Western blot confirmed ablation of the protein.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Braf<exon3->,
  • Braf<exon3->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories