Primary Identifier | MGI:3711007 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Braf |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was removed by cre mediated recombination in the germline. Deletion of exon 3 was expected to cause a reading frame shift and introduce a translational stop codon at position 132, truncating the RBD, CRD and kinase domains. Western blot confirmed ablation of the protein. |