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Allele : Gjb3<tm2.1Kwi> gap junction protein, beta 3; targeted mutation 2.1, Klaus Willecke

Primary Identifier  MGI:3711982 Allele Type  Targeted
Attribute String  Humanized sequence, Modified isoform(s), Null/knockout Gene  Gjb3
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A T to C transition resulted in the insertion of the human F137L mutation in the third transmembrane region. A floxed sequence, including an frt-flanked neo, was located downstream of the F137L mutation and subsequently removed via transient cre expression.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Cx31<F137L>,
  • Cx31<F137L>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories