Primary Identifier | MGI:3711997 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Pax6-cre)1Zkoz |
Strain of Origin | Not Specified | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Three copies of a lens-specific element derived from Pax6 were cloned upstream of the Pax6 P0 minimal promoter. The regulatory element is known to drive expression in the presumptive lens ectoderm as well as the surrounding head ectoderm. The ectoderm enhancer and promoter fragments were used to drive expression of cre recombinase and EGFP, connected through an IRES. Mice were maintained on an FVB/N background. |