| Primary Identifier | MGI:3711456 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Aqp2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert an IRES-cre-ER-neo into exon 4. This insertion resulted in the loss of the protein kinase A phosphorylation site (S256), but the putative apical localization signal remained. RT-PCR demonstrates no expression for the downstream segment of exon 4, however, transcript for the upstream portion including cre recombinase, was detected. |
