| Primary Identifier | MGI:3713105 | Allele Type | Spontaneous |
| Gene | Cryge | Inheritance Mode | Dominant |
| Strain of Origin | (C3H/HeH x 102/El)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The locus contains a murine endogenous retroviral insertion (ERVK) in exon 3, with intact LTR sequences at both ends and a duplicated GGCGGC hexamer at the insertion site. The insertion is located after codon 142 of the ORF. The mutant transcript contains a normal N-terminal domain and a normal third motif, however, the fourth motif is truncated and would not be able to complete the C-terminal domain. RT-PCR confirmed expression of the mutant transcript. |
