|  Help  |  About  |  Contact Us

Allele : Ewsr1<tm1Sblee> Ewing sarcoma breakpoint region 1; targeted mutation 1, Sean Lee

Primary Identifier  MGI:3713772 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, Null/knockout Gene  Ewsr1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked transcriptional stop signal in antisense orientation was inserted into intron 6, exon 7 was fused to human WT1 (lysine, threonine, and serine version termed +KTS) with a C-terminal FLAG tag, and a 3' neo cassette, replacing exons 8 through 11, was inserted by homologous recombination. The absence of endogenous protein product was confirmed by western blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ewsr1<tm1(WT1)Sblee>,
  • Ewsr1<tm1Wtq>,
  • EWS-WT1(+KTS),
  • Ews<->,
  • Ewsr1 KO,
  • Ewsr1<tm1Wtq>,
  • EWS-WT1(+KTS),
  • Ewsr1<tm1(WT1)Sblee>,
  • Ews<->,
  • Ewsr1 KO
Quick Links:
 
Quick Links:
 

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories