| Primary Identifier | MGI:3713799 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Gne |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to change methionine codon 743 (ATG) in exon 12 to threonine (ACG) (p.M743T; formerly described as p.M712T). A loxP sites was inserted into intron 11 and an FRT site flanked neomycin resistance gene cassette and a second loxP site downstream of exon 12. The mutation is the equivalent of the same human mutation associated with hereditary inclusion body myopathy (HIBM) (OMIM:600737). |
