Primary Identifier | MGI:3715536 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(282M13-Ank*M48T)1Kng |
Strain of Origin | FVB/N or (C57BL/6 x CBA)F1/J | Is Recombinase | false |
Is Wild Type | false |
description | Transgene was inserted into the nuclei of fertilized eggs from FVB/N or (C57BL/6 x CBA)F1/J mice. |
molecularNote | A point mutation was made in the Ank gene contained within Tg(282M13)1Kng converting a methionine to a threonine at amino acid position 48. This mutation is commonly found in patients with familial chondrocalcinosis (CCAL2) and has wild-type levels of PPi-transport in vitro. |