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Allele : Pik3ca<tm1Jdo> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1, Julian Downward

Primary Identifier  MGI:3716068 Allele Type  Targeted
Attribute String  Not Specified Gene  Pik3ca
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace threonine 208 with aspartic acid (T208D) and lysine 227 with alanine (L227A) in exon 3. Cre-mediated recombination was used to remove a floxed neo from the locus.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Pik3ca<RBD>,
  • Pik3ca<RBD>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

10 Publication categories