Primary Identifier | MGI:3716083 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pink1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 4-7 were replaced with a pgk-neo cassette via cre mediated recombination, thereby removing the majority of the kinase domain and creating a nonsense mutation at the beginning of exon 8. Northern blot confirmed absence of transcript in mutants. |