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Allele : Tg(Ttr-KLF6)1Fdmn transgene insertion 1, Scott Friedman

Primary Identifier  MGI:3716726 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ttr-KLF6)1Fdmn
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The tranthyretin promoter was fused to the human KLF6 cDNA to induce hepatoyte-specific overexpresson that is two- to three-fold above normal levels. Expression is localized to hepatocytes with variable expression in the choroid plexus of the brain at high transgene copy number. In addition to transgenic line 1, lines 4 and 9 were also made.
  • mutations:
  • Insertion
  • synonyms:
  • TTR1-KLF6,
  • TTR1-KLF6
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories