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Allele : Sox17<tm2Sjm> SRY (sex determining region Y)-box 17; targeted mutation 2, Sean J Morrison

Primary Identifier  MGI:3717121 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Sox17
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Intracranial Aneurysm J:234137.
molecularNote  LoxP sites were inserted on either side of the exon 3-5 region of the Sox17 gene. Mice homozygous for this allele are viable and fertile and do not display any gross physical or behavioral abnormalities. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific expression of the gene.
  • mutations:
  • Insertion
  • synonyms:
  • Sox17<fl>,
  • Sox17<cKO>,
  • Sox17<cKO>,
  • Sox17<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

20 Publication categories