Primary Identifier | MGI:3717419 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(Scx-GFP)1Stzr |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The GFP open reading frame was inserted into exon 1 beginning at the initiator ATG of the Scx gene and replacing most of the first exon. The transgene construct retains the splice donor sequences of exon 1 such that the transcripts of the transgene are spliced to include exon 2. The construct was injected into fertilized eggs and 2 lines were generated that showed robust expression in tendons and tendon progenitors. One line was found to be homozygous viable and was propagated for detailed analysis. |