Primary Identifier | MGI:3719094 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bcl6b |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A region encoding 124 C-terminal amino acids was replaced by a pgk-neo cassette. This deleted region contained all of the zinc finger amino acids, and thus the targeted gene was rendered incapable of producing a DNA binding protein by alternative splicing. RT-PCR confirmed absence of transcript from mutant lungs. |