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Allele : App<tm1Umu> amyloid beta precursor protein; targeted mutation 1, Ulrike C Muller
Primary Identifier  MGI:3718442 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  App
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A stop codon was introduced into exon 16 behind the alpha-secretase site at position QK612, flanked by a SV40 polyA site to ensure efficient polyadenylation of the mRNA. A floxed neo was removed via transient cre expression.
  • mutations:
  • Insertion
  • synonyms:
  • APPs<salpha>,
  • APPsalpha-KI,
  • APPs<salpha>,
  • APPsalpha-KI,
  • APPsalpha<->,
  • APPsalpha<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories





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