Primary Identifier | MGI:3718456 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(SOD1)69Yg |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 14.5 kb fragment of human genomic DNA containing the entire SOD1 gene, including its regulatory sequences, was used for microinjection into fertilized eggs. Line 51 contains 4-5 copies of the transgene and expresses 3-5-fold more superoxide dismutase 1in the brain than non-transgenic mice. |