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Allele : Agtr1a<tm1Ecl> angiotensin II receptor, type 1a; targeted mutation 1, Eric Clauser

Primary Identifier  MGI:3721911 Allele Type  Targeted
Attribute String  Not Specified Gene  Agtr1a
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation was introduced into exon 3 causing an asparagine to serine substitution at amino acid 111 (N111S). A C-terminal deletion of the coding region was also introduced at position 329. A hygro cassette flanked by loxP sites was introduced into 3' UTR of exon 3. Homozygous mice had normal expression of the gene as determined by quantitative RT PCR of several tissues.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • AT1aMUT,
  • AT1aN11S/delta329,
  • AT1aMUT,
  • AT1aN11S/delta329
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories