| Primary Identifier | MGI:3722860 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene |
Tg(Rr158-H2-Ea |
| Strain of Origin | (C57BL/6 x SJL)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A 5.2 kb fragment encoding H2-Ead was ligated 3' of Igk enhancer/promoter sequences Rr158 (Igk-Eik), where the enhancer is a 0.9 kb fragment from the J-C intron. The construct was microinjected into (C57BL/6 x SJL)F2 oocytes. Transgene expression was observed in B-cell areas of the spleen, but density of I-E on spleen and lymph node B-cells was low relative to endogenous I-A or Ig. |
