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Allele : Atp2c1<tm1Ges> ATPase, Ca++-sequestering; targeted mutation 1, Gary E Shull

Primary Identifier  MGI:3722875 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atp2c1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced exons 10-13, which encode both the catalytic phosphorylation domain and transmembrane domains 3 and 4. RT-PCR and sequencing analysis revealed expression of a mutant mRNA in which exon 9 is spliced to exon 14. Western analysis revealed decreased protein expression in heterozygous mice
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Spca1<->,
  • Spca1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories