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Allele : Dnah5<hlb612> dynein, axonemal, heavy chain 5; heart, lung and blood 612

Primary Identifier	MGI:3722326	Allele Type	Chemically induced (ENU)
Gene	Dnah5	Inheritance Mode	Recessive
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

29,755 base pairs containing exons 7 through 17 were deleted by ENU mutgenesis. This resulted in a 593 amino acid deletion in the protein and deletion of the DHC_N1 domain.

mutations:
Intragenic deletion

synonyms:
Dnahc5<del593>,
Dnahc5<del593>,
Mdnah5<del267-859>,
Mdnah5<del267-859>,
Mdnah5<del267-859>

earliestPublication:
Tan SY, et al. (2007) Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia. J Clin Invest 117(12):3742-52

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

6 Publication categories

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