Primary Identifier | MGI:3723646 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Plpp3 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Three stop codons in three framse followed by an IRES-lacZ cassette and a floxed neo cassette were inserted in exon 3 via homologous recombination. The insertion of this construct disrupts the protein between the C1 and C2 domains essential for catalytic activity. |