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Allele : Dbx1<tm1(DTA)Apie> developing brain homeobox 1; targeted mutation 1, Alessandra Pierani

Primary Identifier  MGI:3757953 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Dbx1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES floxed PGK-neo cassette and the diphtheria toxin (DTA) gene were inserted in the downstream untranslated portion of the gene. Multiple stop codons in the PGK-neo cassette prevent translation read-through of the diphtheria toxin gene. Functional DTA is expressed upon Cre-mediated recombination.
  • mutations:
  • Insertion
  • synonyms:
  • Dbx1<loxP-stop-loxP-DTA>,
  • Dbx1<DTA>,
  • Dbx1<loxP-stop-loxP-DTA>,
  • Dbx1<IRES-loxP-Stop-loxP-DTA>,
  • Dbx1<DTA>,
  • Dbx1<IRES-loxP-Stop-loxP-DTA>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

16 Publication categories